Injectables vs. Daily PrEP?
Trying to decide between daily PrEP pills and long-acting injectable PrEP? Both provide excellent protection against HIV, but they differ in how you take them, how widely available they are, and what kind of care experience they offer.
And the most important thing to know?
You don’t have to wait for injectables to start protecting yourself.
Important Note About PrEP: PrEP (Pre-Exposure Prophylaxis)—whether taken as a daily oral pill or as an injectable option—is for people who are HIV-negative and want to prevent HIV. It is not a treatment for people living with HIV. If you are living with HIV and need affirming, judgment-free care, Kind Clinic is here for you. Give us a call at (833-937-5463) to make an appointment and start HIV care with us.
Daily Oral PrEP Pills: The Most Accessible Way to Stay Protected
Long-Acting Injectable PrEP: Protection That Lasts
Injectable PrEP like Yeztugo offer:
- As few as two injections per year
- No daily reminders
- A discreet, low-maintenance option
But here’s the key: Injectable PrEP is not yet widely available in many non-profit, community-based clinics nationwide—including Kind Clinic—because access, pharmacy distribution, and insurance coverage are still developing. They are coming, and the future is bright. But today, access is limited.
So, What Should You Choose?
Choose daily PrEP pills NOW:
- Coverage that already exists
- Fast, simple access
- A pathway to switch to injectables later
Choose Injectable PrEP LATER if you want:
- Long-term protection with few appointments
- A pill-free routine
- Discreet HIV prevention
Kind Clinic Makes the Journey Easy
Our commitment to our patients centers on getting you protected as quickly as possible. Here’s how:1. Start with daily pills—it’s fast and accessible.
If you are HIV-negative, you’ll receive a PrEP prescription at your appointment, and we’ll help you get it delivered or picked up from one of our partner pharmacies.2. We monitor injectable PrEP developments for you.
Insurance coverage updates. Availability updates. Pharmacy access. We stay on top of it.3. When injectable PrEP expands, we will transition you seamlessly.
You won’t have to figure it out alone—once you and your provider decide it’s the right option for you, we’ll guide you through every step.
Bottom Line: Start Now. Switch Later. We’ve Got You.
Yeztugo (Lenacapavir): Long-Acting Injectable PrEP FAQs
Important Note About PrEP: PrEP (Pre-Exposure Prophylaxis)—whether taken as a daily oral pill or as an injectable option—is for people who are HIV-negative and want to prevent HIV. It is not a treatment for people living with HIV. If you are living with HIV and need affirming, judgment-free care, Kind Clinic is here for you. Give us a call at (833-937-5463) to make an appointment and start HIV care with us.
Daily PrEP pills remain the most widely available and accessible form of HIV prevention. If you’re interested in injectable PrEP, don’t wait—start protecting yourself now with daily pills, and when injectable PrEP becomes available and covered by your insurance, we’ll help you transition seamlessly. Kind Clinic works with you, your provider, and your insurance to get you on the prevention option that fits your needs.
All FDA-approved forms of PrEP—Truvada, Descovy, Apretude, and Yeztugo (lenacapavir)—are highly effective at preventing HIV. Our job is to help you access the option that works best for you. Injectable PrEP is one of several PrEP methods that provides HIV prevention without taking a daily pill. Yeztugo, a twice-a-year injection, represents a major step forward, and other options like Apretude are also FDA-approved injectables.
Below are FAQs on Yeztugo, the most recently approved injectable PrEP option and the first two-shot per year method.
Are injectables like Yeztugo available at Kind Clinic?
Injectable PrEP is not yet widely available in many non-profit, community-based clinics nationwide like Kind Clinic. But they are coming, and Kind Clinic is actively preparing systems, training, and insurance workflows to offer them as soon as they become accessible. We are your trusted PrEP provider and expert in sexual health—start with us, and we’ll move with you into the future of HIV prevention.
What is Yeztugo and how does it help me stay HIV-free?
Yeztugo is a long-acting injection given twice a year to prevent HIV through sex. It’s a form of PrEP that offers powerful, long-lasting protection with just two doses per year. Review the full prescribing information and patient information about Yeztugo.
How often do I need Yeztugo?
After a one-time starter regimen (pills + injections), you receive two injections per year, every six months.
Who can use Yeztugo?
Yeztugo is approved for pre-exposure prophylaxis (PrEP) in adults and adolescents who weigh at least 35 kg (about 77 lbs) and test HIV-1 negative, regardless of gender identity. Its use during pregnancy has been studied only to a limited extent, so prescribing should involve weighing potential risks and benefits, as with any antiretroviral therapy in pregnancy.
Does Yeztugo affect my hormones or gender-affirming care?
No. Yeztugo does not interfere with hormone therapy or gender-affirming treatments.
What does the PrEP injection feel like?
It goes just under the skin. You may feel brief stinging, and a small bump can form—normal signs the medication is releasing over time.
What if I miss a dose of a PrEP injection?
Contact your provider. You may need temporary oral PrEP or to adjust your schedule. Staying consistent ensures full protection.
Does Yeztugo protect against other STIs?
No. It protects only against HIV. Condoms, regular STI screenings, and other safer-sex strategies are still recommended.
How effective is Yeztugo?
Clinical trials show 99% effectiveness. In some studies, no one receiving Yeztugo acquired HIV.
Is Yeztugo covered by insurance?
Coverage is expanding but still in early stages. Many plans are expected to add coverage as adoption grows.
Apretude (cabotegravir): Long-Acting Injectable PrEP — FAQs
Important Note About PrEP: PrEP (Pre-Exposure Prophylaxis)—whether taken as a daily oral pill or as an injectable option—is for people who are HIV-negative and want to prevent HIV. It is not a treatment for people living with HIV. If you are living with HIV and need affirming, judgment-free care, Kind Clinic is here for you. Call us at 833-937-5463 to make an appointment and begin HIV care with us.
Daily PrEP pills remain the most widely available and accessible HIV prevention method. If you’re interested in injectable PrEP, don’t wait—start protecting yourself now with daily pills, and when injectable PrEP is available and covered by your insurance, we’ll help you transition seamlessly. Kind Clinic works closely with you, your provider, and your insurance to get you on the prevention option that best fits your needs.
All FDA-approved forms of PrEP—Truvada, Descovy, Apretude, and Yeztugo (lenacapavir)—are highly effective at preventing HIV. Our job is to help you access the option that works best for your lifestyle. Apretude, a long-acting injectable taken every two months, offers a powerful alternative for people who don’t want to take a daily pill.
Below are FAQs about Apretude, the first FDA-approved long-acting injectable PrEP option.
Are PrEP injectables like Apretude available at Kind Clinic?
Injectable PrEP is not yet widely available in many nonprofit, community-based clinics like Kind Clinic. But they are coming—and we are actively preparing our systems, training, and insurance workflows so we can offer injectable PrEP as soon as it becomes broadly accessible. We are your trusted PrEP provider and sexual-health expert—start with us, and we’ll guide you into the future of HIV prevention.
What is Apretude and how does it help me stay HIV-free?
Apretude (cabotegravir) is a long-acting injection designed to prevent HIV through sex. After a short initiation phase, you receive an injection every two months, offering continuous, highly effective protection without needing a daily pill. Review the full prescribing information and patient information for Apretude.
How often do I need Apretude?
You’ll begin with a one-time “starter” phase:
- An optional oral lead-in (cabotegravir pills) for about 4 weeks, or
- You may go straight to injections if you and your provider decide it’s right for you.
After your first two injections given one month apart, Apretude is administered every two months.
Who can use Apretude?
Apretude is approved for pre-exposure prophylaxis (PrEP) in adults and adolescents who weigh at least 35 kg (about 77 lbs) and test HIV-1 negative, regardless of gender identity. Its use during pregnancy has been studied only to a limited extent, so prescribing should involve weighing potential risks and benefits, as with any antiretroviral therapy in pregnancy.
Does Apretude affect my hormones or gender-affirming care?
No. Apretude does not interfere with hormone therapy or other gender-affirming treatments.
What does the PrEP injection feel like?
Apretude is injected into the muscle of your buttock. You may feel pressure or brief soreness afterward—common effects of an intramuscular injection. Some people experience swelling or tenderness at the injection site, which usually resolves quickly.
What if I miss a dose of a PrEP injection?
Contact your provider right away. You may need oral PrEP as a temporary backup or a schedule adjustment to maintain full protection.
Does Apretude protect against other STIs?
No. Apretude only protects against HIV. Condoms, regular STI screenings, and other safer-sex strategies are still recommended.
How effective is Apretude?
Clinical trials show Apretude to be 99% effective at preventing HIV when taken on schedule.
Is Apretude covered by insurance?
Coverage is expanding but still in early stages. Many plans are expected to add coverage for injectable PrEP as adoption grows.